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Dianette (cyproterone acetate and ethinylestradiol)

Dianette is a specialised oral contraceptive for the treatment of acne and abnormal hair growth (hirsutism) in women.

What is Dianette?

Dianette is an oral contraceptive, it contains an oestrogen and an anti-androgen, and is a very effective treatment for acne and hirsutism.

Your body makes both male and female sex hormones. Male hormones (androgens) stimulate the grease-glands in your skin and hairs that grow from it. If you produce too much androgen, or if you are particularly sensitive to their effects, the grease glands may produce too much sebum. This can block the grease-glands, which can become infected and inflamed causing acne spots. The main action of a special hormone in this medicine (cyproterone acetate) stops androgens affecting the skin. Your medicine also reduces the amount of hormones, including androgens, which are produced.

What is it used for:


  • Severe acne which hasn’t improved after the long-term use of oral antibiotics in women.
  • Excessive hair growth on the face and body (hirsutism) in women.
  • Numerous medical papers demonstrate that oestrogen and cyproterone acetate are effective in the treatment of female hair loss.

Studies have shown that Dianette used for 6-9 months clearly decreases hair loss and hair thinning[1]. Acne and seborrhoea improved after 3-4 cycles; alopecia (hair loss) after 8-9 cycles and hirsutism diminished after 3 cycles of treatment[2] The rate of success (of Dianette) was 94% for acne, 85% for hirsutism and 55% for alopecia[3].

Oral contraceptives work in three ways: by preventing an egg being released from your ovaries; by making the fluid (mucus) in your cervix thicker, which makes it more difficult for sperm to enter the womb; and by preventing the lining of your womb thickening enough for an egg to grow in it. Dianette is a 21-day pill – you take one each day for 21 days, followed by 7 days when you take no pills.

In studies, women taking cyproterone-acetate and ethinyl-oestradiol (Dianette) for female pattern hair loss ended up with significantly reduced B12 and serum ferritin levels. Patients taking cyproterone acetate and ethinyl-oestradiol (Dianette) responded best (hair re growth) when their serum ferritin levels were greater than 40 micrograms/L. [4,5] Therefore we highly recommend patients should take Florisene therapy while on Dianette.

The benefits of taking an oral contraceptive include:


  • It is one of the most reliable reversible methods of contraception if used correctly
  • It doesn’t interrupt sex
  • It usually makes your periods regular, lighter and less painful
  • It may help with pre-menstrual symptoms.
  • You do not have to take any other oral contraceptive while you are taking Dianette.
  • Dianette will not protect you against sexually transmitted infections, such as Chlamydia or HIV. Only condoms can help to do this.

How can I buy Dianette online

You can buy Dianette online with or without a prescription at medical specialists, after completing a simple online consultation. If you prefer to order Dianette UK over the phone, just give us a call and we will be pleased to help. We are the UK’s leading supplier of acne, excessive hair, and hair loss treatment, and Dianette for sale in the UK by a pharmacy is regulated by the General Pharmaceutical Council.

References:

1. Brzezińska-Wcisło L. (2003) "Assessment of efficacy of Diane-35 (Dianette) in androgenetic feminine alopecia." Wiad Leek. 2003;56(3-4):202-5. PMID 12923971

2. Erdmann D. et al (1994) "Ovarian suppression with Diane 35/50." Geburtshilfe Frauenheilkd. 54(11):627-33. PMID 8719015

3. Ekoe JM. et al (1980) "Treatment of hirsutism, acne and alopecia with cyproterone acetate." Dermatologica. 160(6):398-404. PMID 6446466

4. Ramsay ID, Rushton DH. (1990)"Reduced serum vitamin B12 levels during oral cyproterone-acetate and ethinyl-oestradiol therapy in women with diffuse androgen-dependent alopecia." Clin Exp Dermatol. 15(4):277-81. PMID 2145099

5.Rushton DH, Ramsay ID. (1992) "The importance of adequate serum ferritin levels during oral cyproterone acetate and ethinyl oestradiol treatment of diffuse androgen-dependent alopecia in women." Clin Endocrinol (Oxf). 36(4):421-7. PMID 1424176

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